Dennis E Kyle Selected Research

N1- (7- chloro- quinolin- 4- yl)- 2- methyl- propane- 1,2- diamine

9/2012

Novel 4-aminoquinoline analogs highly active against the blood and sexual stages of Plasmodium in vivo and in vitro.

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Dennis E Kyle Research Topics

Disease

34	Malaria 01/2024 - 01/2002
5	Vivax Malaria 01/2022 - 11/2005
5	Infections 01/2022 - 10/2007
5	Falciparum Malaria (Plasmodium falciparum Malaria) 01/2019 - 03/2004
4	Parasitemia 12/2018 - 11/2005
2	Communicable Diseases (Infectious Diseases) 01/2021 - 06/2020
2	Parasitic Diseases (Parasitic Disease) 01/2020 - 01/2009
2	Body Weight (Weight, Body) 09/2012 - 08/2009
1	Hepatocellular Carcinoma (Hepatoma) 11/2023
1	Melanoma (Melanoma, Malignant) 10/2023
1	Cryptosporidiosis 01/2019
1	Meningoencephalitis 01/2019
1	Carcinoma (Carcinomatosis) 10/2017
1	Visceral Leishmaniasis (Kala Azar) 06/2014
1	Piedra (Piedras) 01/2009
1	Leukemia L1210 05/2002
1	Leishmaniasis 01/2002

Drug/Important Bio-Agent (IBA)

13	Antimalarials (Antimalarial Agents)IBA 11/2023 - 03/2004
11	artemisinin (artemisinine)IBA 01/2019 - 03/2004
3	Chloroquine (Aralen)FDA LinkGeneric 01/2018 - 01/2009
3	ArtesunateIBA 01/2014 - 03/2004
2	VaccinesIBA 12/2022 - 01/2017
2	Proteins (Proteins, Gene)FDA Link 01/2021 - 01/2015
2	artemisoneIBA 01/2019 - 08/2009
2	Mefloquine (Lariam)FDA LinkGeneric 06/2010 - 08/2009
1	muconomycin AIBA 01/2024
1	verrucarolIBA 01/2024
1	diacetoxyscirpenolIBA 01/2024
1	DNA (Deoxyribonucleic Acid)IBA 10/2023
1	Interferon Type IIBA 01/2022
1	Cre recombinaseIBA 01/2022
1	8-aminoquinolineIBA 01/2022
1	EpitopesIBA 11/2021
1	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 11/2021
1	Recombinant ProteinsIBA 01/2021
1	Ether (Diethyl Ether)IBA 01/2021
1	ProdrugsIBA 01/2021
1	DiterpenesIBA 06/2020
1	ArtemisininsIBA 01/2019
1	posaconazole FDA Link 01/2019
1	Lysine-tRNA LigaseIBA 01/2019
1	Primaquine FDA Link 10/2017
1	coumarinIBA 10/2017
1	Fluorescent Dyes (Fluorescent Probes)IBA 10/2017
1	menoctoneIBA 01/2017
1	Cytochromes b (Cytochrome b)IBA 01/2017
1	Peptide Elongation Factor 2 (EF-2)IBA 01/2015
1	Messenger RNA (mRNA)IBA 01/2015
1	Guanosine Triphosphate (GTP)IBA 01/2015
1	DDD107498IBA 01/2015
1	SJ733IBA 12/2014
1	QuinazolinesIBA 06/2014
1	pyronaridineIBA 01/2014
1	Drug CombinationsIBA 01/2014
1	succinyl-trialanine-4-nitroanilide (SANA)IBA 01/2014
1	Complex MixturesIBA 12/2013
1	6- Chloro- 7- methoxy- 2- methyl- 3- (4- (4- (trifluoromethoxy)phenoxy)phenyl)quinolin- 4(1H)- oneIBA 03/2013
1	4-aminoquinolineIBA 09/2012
1	N1- (7- chloro- quinolin- 4- yl)- 2- methyl- propane- 1,2- diamineIBA 09/2012
1	N1- (7- chloro- quinolin- 4- yl)- 2,N2,N2- trimethylpropane- 1,2- diamineIBA 09/2012
1	quinolineIBA 09/2012
1	Ion Channels (Ion Channel)IBA 07/2012
1	Propafenone (Rythmol)FDA LinkGeneric 07/2012
1	ICI 56,780IBA 12/2011
1	AcidsIBA 11/2007
1	thymidylate synthase-dihydrofolate reductaseIBA 10/2007
1	proguanil drug combination atovaquone (malarone)FDA Link 10/2006
1	Azithromycin (Zithromax)FDA LinkGeneric 11/2005
1	Artemether FDA Link 03/2004
1	Cyclin-Dependent Kinases (cdk Proteins)IBA 08/2003
1	triptyceneIBA 05/2002
1	Angiogenesis InhibitorsIBA 01/2002
1	methionine aminopeptidase 2IBA 01/2002

Therapy/Procedure

10	Therapeutics 01/2019 - 01/2011
1	Oral Administration 01/2019
1	Drug Therapy (Chemotherapy) 01/2017